Registro monocentrico per il monitoraggio dei nuovi anticoagulanti orali (NAO) nella prevenzione dell'ictus in pazienti anziani affetti da fibrillazione atriale non valvolare (FANV)

Luca Fallavollita, Elpidio Santillo, Luciano Marini, Fabrizio Balestrini

Abstract

Atrial Fibrillation (AF) is the most frequently diagnosed arrhythmia in population.

Its prevalence increases with age with as many as 8.8% of people older than 80 years are affected.

Stroke is the most feared consequence of AF. Anticoagulation oral therapy with warfarin has been used clinically for many decades. However in recent years the international scenario has significantly changed since of the advent of new oral anticoagulants (NAO): dabigatran, rivaroxaban and apixaban.

The efficacy and safety of the NAO have been tested in randomized clinical trials. Data from real world are needed to extend the conclusions of the clinical trials to larger population, including the elderly.

The present article provides preliminary data from our observational registry of use of NAO in the elderly with FANV.